SBS 2007 - Poster Presented
At the 2007 annual conference of the Society for Biomolecular Sciences, AnaSpec presented a technical poster that documented the sensitivity of its new SensoLyteTM renin assay kits utilizing FRET peptide substrates.
The poster documented the following conclusions:
- AnaSpec's development of a pair of sensitive renin activity assay kits including an ultra-sensitive renin assay based on a QXLTM 520/5-FAM FRET substrate.
- Assay with QXLTM 520/5-FAM substrate was approximately 40 fold more sensitive than an existing assay which uses an EDANS/DABCYL FRET substrate and 10 fold more sensitive than the Dnp/Amp based assay.
- The longer excitation and emission wavelengths 5-FAM minimize the interference from the autofluorescence of test compounds.
- The newly developed assays can be used to detect renin activity and can be applied to the high throughput screening of renin inhibitors.
To view the full poster, click here
For a listing of SensoLyteTM Renin Assay Kits, click here