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Fluorescent Dyes  >  Reactive Fluorescent Dyes  >>  N-(1-Pyrene)maleimide

Product Name N - (1 - Pyrene)maleimide
Size 100 mg
Catalog # AS-81436
US$ $93
Description

N-(1-Pyrene)maleimide is an UV excitable thiol-reactive fluorophore that is widely used to develop ratiometric fluorescent membrane probes. In general, pyrene fluorophores have concentration-dependent fluorescence due to the formation of excimer.

Minimum Purity: 95%

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C desiccated and protected from light
References Ohyashiki T, et al. (1989). Changes in the fluorescence characteristics of N-(1-pyrene) maleimide bound to the intestinal brush-border membranes by neuraminidase treatment. Chem Pharm Bull (Tokyo) 37, 2165-9; Sedgwick EG, et al. (1997). Cross-linking and N-(1-pyrenyl)maleimide labeling of cysteine mutants of proton-pumping pyridine nucleotide transhydrogenase of Escherichia coli. Biochemistry 36, 15285-93.
Molecular Weight 297.31
Spectral Properties Abs/Em = 338/375 nm
Solvent System DMF or DMSO
Product Citations Grintsevich, E. et al. (2010). Antiparallel Dimer and Actin Assembly. Biochem 49, 3919.
Stratton, M. et al. (2008). A Ca2+-Sensing Molecular Switch Based on Alternate Frame Protein Folding. ACS Chem Biol 3, 723.
     
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