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Assay Kits  >  MMP Assay Kits  >>  SensoLyte® Plus 520 MMP-1 Assay Kit *Fluorimetric and Enhanced Selectivity*

Product Name SensoLyte® Plus 520 MMP - 1 Assay Kit *Fluorimetric and Enhanced Selectivity*
Size 1 kit
Catalog # AS-72012
US$ $561
Description

The SensoLyte® Plus 520 MMP-1 Assay Kit is designed for specifically detecting MMP-1 activity in biological samples which may contain multiple MMPs, such as culture medium, serum, plasma, synovial fluid, and tissue homogenate. A specific anti-MMP-1 monoclonal antibody is used in combination with an MMP fluorogenic substrate, 5-FAM/QXL®520 FRET peptide. The fluorescence signal is monitored at Ex/Em=490 nm/520 nm upon MMP-1-induced cleavage of the FRET substrate. Ample materials are provided to perform 96 assays in a 96-well format.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
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Jian, J. et al. (2011). Iron sensitizes keratinocytes and fibroblasts to UVA-mediated matrix metalloproteinase-1 through TNF-α and ERK activation. Exp Dermatol 20, 249.
Moor, A. et al. (2009). Proteolytic activity in wound fluids and tissues derived from chronic venous leg ulcers. Wound Repair Regen 17, 832.
Shi, Z-D. et al. (2009). Interstitial flow promotes vascular fibroblast, myofibroblast, and smooth muscle cell motility in 3-D collagen I via upregulation of MMP-1. Am J Physiol Heart Circ Physiol 10.1152/ajpheart.00369.2009.
     
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