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Peptides  >  Cell Permeable Peptides (CPP) / Drug Delivery Peptides  >>  MPGΔNLS, HIV related;

Product Name MPGΔNLS, HIV related;
GALFLGFLGAAGSTMGAWSQPKSKRKV
Size 1 mg
Catalog # 60633
US$ $363
Description

This 27-residue peptide, designated MPGΔNLS,is derived from the hydrophobic fusion peptide of HIV-1 gp41 (for efficient crossing of the cell membrane) and the hydrophilic nuclear localization sequence of SV40 large T antigen (for the nuclear addressing of the peptide). MPGΔNLS contains a single mutation in which the second lysine in the NLS has been mutated to serine.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20C
References Deshayes, S. et al. Adv. Drug Deliv. Rev. 60, 537 (2008); Morris, M. et al. Nucleic Acids Res. 27, 3510 (1999); Simeoni, F. et al. Nucleic Acids Res. 31, 2717 (2003).
Molecular Weight 2766.2
Sequence
(One-Letter Code)
GALFLGFLGAAGSTMGAWSQPKSKRKV
Sequence
(Three-Letter Code)
H - Gly - Ala - Leu - Phe - Leu - Gly - Phe - Leu - Gly - Ala - Ala - Gly - Ser - Thr - Met - Gly - Ala - Trp - Ser - Gln - Pro - Lys - Ser - Lys - Arg - Lys - Val - OH
Product Citations Fukuyama, Y. et al. (2012). Alkylated dihydroxybenzoic acid as a MALDI matrix additive for hydrophobic peptide analysis. Anal Chem 84, 4237.
     
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