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Peptides  >  Cell Permeable Peptides (CPP) / Drug Delivery Peptides  >>  Membrane-Permeable Sequence, MPS

Product Name Membrane - Permeable Sequence, MPS
AAVALLPAVLLALLAK
Size 1 mg
Catalog # AS-61218
US$ $99
Description

This peptide corresponds to the membrane-permeable sequence designed from the carboxyl terminus of Gα subunits targeting G protein subunits. This is a membrane-translocating hydrophobic sequence derived specifically from the h-region of a signal peptide sequence of K-FGF (Kaposi fibroblast growth factor).

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References 1, Orr, A. et al. J. Biol. Chem. 277, 20453 (2002)
2, Lin Y-Z. et al. J Biol Chem. 270, 14255-14258 (1995).
Molecular Weight 1547
Sequence
(One-Letter Code)
AAVALLPAVLLALLAK
Sequence
(Three-Letter Code)
H - Ala - Ala - Val - Ala - Leu - Leu - Pro - Ala - Val - Leu - Leu - Ala - Leu - Leu - Ala - Lys - OH
Product Citations Bartz, R. et al. (2011). Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape. Biochem J 435, 475. doi:10.1042/BJ20101021.
Nino, G. et al. (2009). Mechanism regulating pro-asthmatic effects of prolonged homologous {beta}2-adrenergic receptor desensitization in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol297, L746. doi:10.1152/ajplung.00079.2009.
Orr, A W. et al. (2002). Thrombospondin stimulates focal adhesion disassembly through Gi- and phosphoinositide 3-kinase-dependent ERK activation. J Biol Chem277, 20453.
     
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