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Peptides  >  Myelin Oligodendrocyte Glycoprotein (MOG)/Myelin Basic Proteins (MBP)  >>  MOG (40–54)

Product Name MOG (40–54)
YRSPFSRVVHLYRNG
Size 1 mg
Catalog # 61626
US$ $93
Purity % Peak Area By HPLC ≥ 95%
Description

This truncated myelin oligodendrocyte glycoprotein ( MOG) peptide, was tested to identify the core encephalitogenic epitope of CD8+ MOG-specific T cells, it’s binding to recombinant H-2Db dimers and the ability to induce experimental autoimmune encephalomyelitis (EAE). This peptide strongly binds recombinant H-2Db protein and this complex bound MOG-specific CD8+ T cells. The minimal, functionally constant MOG peptide that binds to CD8+ MOG-specific T cells and stimulates T cell proliferation in vitro, MOG(44–54), is within this sequence.

Storage -20°C
References Ref: Sun, D. et al. Int. Immunol 15, 261(2003)
Molecular Weight 1851.1
Sequence
(One-Letter Code)
YRSPFSRVVHLYRNG
Sequence
(Three-Letter Code)
H - Tyr - Arg - Ser - Pro - Phe - Ser - Arg - Val - Val - His - Leu - Tyr - Arg - Asn - Gly - OH
     
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