Login
Existing Account

Please login first to complete purchase/ quotation request, view custom order reports, or create favorites list.

Customer ID:
Password:
Stay Logged In


Forgot your Customer ID or Password?
New Account

Don't have an account with us yet? Please set up an account to place order or obtain customer services.

Peptides  >  Cell Permeable Peptides (CPP) / Drug Delivery Peptides  >>  [Cys58]105Y, Cell Penetrating Peptide, α1-antitrypsin (358-374)

Product Name [Cys58]105Y, Cell Penetrating Peptide, α1 - antitrypsin (358 - 374)
CSIPPEVKFNKPFVYLI
Size 1 mg
Catalog # AS-62005
US$ $105
Description

This is a synthetic peptide based on the sequence corresponding to residues 359 to 374 of α1-antitrypsin. C105Y can penetrate cell membrane rapidly, enter the cytoplasm, and localize to the nucleus and nucleolus of live culture cells. C105Y peptide is routed to the nucleolus very rapidly in an energy-dependent fashion; whereas membrane translocation and nuclear localization are energy-independent. It enhances gene expression from DNA nanoparticles.

Storage -20C
References M. Rhee and P. Davis J. Biol. Chem. 281, 1233 (2006).
Molecular Weight 1994.4
Sequence
(One-Letter Code)
CSIPPEVKFNKPFVYLI
Sequence
(Three-Letter Code)
H - Cys - Ser - Ile - Pro - Pro - Glu - Val - Lys - Phe - Asn - Lys - Pro - Phe - Val - Tyr - Leu - Ile - OH
Product Citations Bartz, R. et al. (2011). Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape. Biochem J doi:10.1042/BJ20101021.
     
  < Back