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Peptides  >  Cell Permeable Peptides (CPP) / Drug Delivery Peptides  >>  TAT-NSF222 Fusion Peptide

Product Name TAT - NSF222 Fusion Peptide
YGRKKRRQRRR - GGG - LDKEFNSIFRRAFASRVFPPE
Size 1 mg
Catalog # 62240
US$ $313
Description

This sequence is N-ethyl-maleimide-sensitive factor (NSF) peptide connected to 11 amino acid cell permeable human immunodeficiency virus (HIV) transactivating regulatory protein (TAT) domain by Gly-Gly-Gly spacer. This peptide contains NSF domain extending from amino acids 222 to 243, which is directly amino-terminal of the Walker A motif of the D1 domain of NSF. ATPase assay shows that TAT-NSF222 inhibits NSF ATPase activity.

Storage -20C
References Matsushita, K. et al. Mol. Pharmacol. 67,1137 (2005).
Molecular Weight 4239.9
Sequence
(One-Letter Code)
YGRKKRRQRRR-GGG-LDKEFNSIFRRAFASRVFPPE
Sequence
(Three-Letter Code)
H - Tyr - Gly - Arg - Lys - Lys - Arg - Arg - Gln - Arg - Arg - Arg - Gly - Gly - Gly - Leu - Asp - Lys - Glu - Phe - Asn - Ser - Ile - Phe - Arg - Arg - Ala - Phe - Ala - Ser - Arg - Val - Phe - Pro - Pro - Glu - OH
Product Citations Trang, T. et al. (2009). P2X4-Receptor-Mediated Synthesis and Release of Brain-Derived Neurotrophic Factor in Microglia Is Dependent on Calcium and p38-Mitogen-Activated Protein Kinase Activation. J Neurosci 29, 3518.
Matsushita, K. et al. (2005). A Novel Class of Fusion Polypeptides Inhibits Exocytosis. Mol Pharmacol 67, 1137.
     
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