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Peptides  >  Fluorescent Labeled Peptides  >>  Cls Substrate, C2 (5-FAM/ QXL 520)

Product Name Cls Substrate, C2 (5 - FAM/ QXL 520)
5 - FAM - SLGRKIQIQ - K(QXL 520) - NH2
Size 0.5 mg
Catalog # 61314
US$ $231
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is a second complement component (C2), the physiological substrate for the proenzyme Cls, first complement component. The complement system is a central component of host defense but can also contribute to the inflammation seen in pathological conditions. The C1s protease of the C1 complex initiates the host defense pathway. This peptide employs 5FAM/QXL520 FRET pair for quantitation of complement enzyme activity.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
Molecular Weight 2019.2
Sequence
(One-Letter Code)
5-FAM-SLGRKIQIQ-K(QXL520)-NH2
Sequence
(Three-Letter Code)
5 - FAM - Ser - Leu - Gly - Arg - Lys - Ile - Gln - Ile - Gln - Lys(QXL520) - NH2
Product Citations Arnoczky, S.P. et al. Am. J. Sports Med. 35, 763 (2007).
     
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