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Peptides  >  Myelin Oligodendrocyte Glycoprotein (MOG)/Myelin Basic Proteins (MBP)  >>  MOG (50-74), human

Product Name MOG (50 - 74), human
LYRNGKDQDGDAPEYRGRTELLKD
Size 1 mg
Catalog # 64216
US$ $198
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide sequence is found in residues 50 to 74 of MOG (Myelin Oligodendrocyte Glycoprotein). This HLA-DR4-restricted epitope play a major role in destabilizing myelin through myelin basic protein breakdown mediated by neutral proteases and thus have an important role in the pathogenesis of MS through the studies of the secretion of IFN-gamma, IL-4, IL-5, and IL-10.

Storage -20C
References Correale, J. et al. Multiple Sclerosis 12, 412 (2006).
Molecular Weight 2810
Sequence
(One-Letter Code)
LYRNGKDQDGDAPEYRGRTELLKD
Sequence
(Three-Letter Code)
H - Leu - Tyr - Arg - Asn - Gly - Lys - Asp - Gln - Asp - Gly - Asp - Ala - Pro - Glu - Tyr - Arg - Gly - Arg - Thr - Glu - Leu - Leu - Lys - Asp - OH
     
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