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Peptides  >  Tubulin Peptides  >>  [Lys(Ac)40]-Ac-a-Tubulin (29-50)-WGK(Biotin); TubK40(Ac)-WGK, biotin-labeled

Product Name [Lys(Ac)40] - Ac - a - Tubulin (29 - 50) - WGK(Biotin); TubK40(Ac) - WGK, biotin - labeled
Ac - GIQPDGQMPSD - K(ac) - TIGGGDDSFNWG - K(biotin)
Size 0.25 mg
Catalog # AS-65411-025
US$ $121
Description

This is an acetylated alpha tubulin peptide at lysine 40 with a C-terminal WG linker followed by a biotinylated lysine. The acetylation at lysine 40 of this peptide is shown to have a therapeutic interest in diseases involving altered intracellular transport such as Huntington's disease. Histone Deacetylase (HDAC) inhibitors have been shown to increase vesicular transport of brain derived neurotrophic factor thereby increasing acetylation of tubulin at lysine 40.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References Dompierre JP. et al. J Neurosci 27(13):3571-3583 (2007).
Molecular Weight 2918.2
Sequence
(One-Letter Code)
Ac-GIQPDGQMPSD-K(ac)-TIGGGDDSFNWG-K(biotin)
     
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