Peptides  >  Myelin Oligodendrocyte Glycoprotein (MOG)/Myelin Basic Proteins (MBP)
Myelin Oligodendrocyte Glycoprotein (MOG), a 26- to 28-kDa protein, is a member of the immunoglobulin superfamily. It is expressed exclusively in the central nervous system (CNS), specifically on the surface of myelinating oligodendrocytes and external lamellae of myelin sheath. Although MOG protein constitutes only 0.01-0.05% of the CNS myelin proteins, it was demonstrated that MOG protein is a crucial autoantigen for multiple sclerosis in humans and experimental autoimmune encephalomyelitis (EAE) in rodents and monkeys.

Myelin Basic Protein (MBP) is the major constituent of the CNS myelin synthesized by oligodendrocytes and Schwann cells. MBP, PLP (proteolipid proteins) and MOG (myelin oligodendrocyte glycoprotein) are potential primary encephalitogenic target antigens in multiple sclerosis.


Ref: Linares, D. et al. Protein Expression and Purif. 34, 249 (2004); Bettadapura, J. et al. J. Neurochem. 70, 1593 (1998); Oliver, AR. et al J. Immunol. 171, 462 (2003); Von Budingen, H-C. et al. J. Clin. Immunol. 21, 155 (2001); Lyons, J-A. et.al. Eur. J. Immunol. 29, 3432 (1999); Von Budingen, H-C. et.al. Eur. J. Immunol. 34, 2072 (2003); Grima, B. et al. J. Neurochem. 59, 2318 (1992); Tabira, TJ. and I. Kira, Strain and species differences of encephalitogenic determinants of myelin basic protein and proteolipid apoprotein. RE. Martenson, ed. Myelin: Biology and Chemistry 783. CRC Press, Boca Raton (1992). De Rosbo, NK. et al. J. Immunol. 173, 1426 (2004).
Related Products:

SensoLyte Anti-MOG (1-125) IgG and Anti-MOG (35-55) IgG ELISA Assay Kits
 Product Size Catalog # US$  
MOG (35 - 55), mouse, rat
MEVGWYRSPFSRVVHLYRNGK
1 mg AS-60130-1 $140
MOG (35 - 55), mouse, rat
MEVGWYRSPFSRVVHLYRNGK
5 mg AS-60130-5 $440
MOG (35 - 55), mouse, rat  NEW
MEVGWYRSPFSRVVHLYRNGK
10 mg AS-60130-10 $800
MOG (35 - 55), human
MEVGWYRPPFSRVVHLYRNGK
1 mg AS-63918 $143
MOG (8 - 21)
PGYPIRALVGDEAE
1 mg AS-62369 $93
MOG (89 - 113), human
RFSDEGGFTCFFRDHSYQEEAAMEL
1 mg AS-64218 $198
MOG (71 - 90), mouse
LLKETISEGKVTLRIQNVRF
1 mg AS-64892 $110
MOG (92106)
DEGGYTCFFRDHSYQ
1 mg AS-62732 $93
MOG (101 - 120), human, mouse
RDHSYQEEAAMELKVEDPFY
1 mg AS-62370 $121
MBP (120), Myelin Basic Protein (1 - 20)
ASQKRPSQRSKYLATASTMD
1 mg AS-62730 $121
MBP (4 - 14)
QKRPSQRSKYL
5 mg AS-22916 $193
MBP (6381), Myelin Basic Protein (6381)
ARTTHYGSLPQKSQRSQ
1 mg AS-62082 $105
MBP (6886), Myelin Basic Protein (6886)
YGSLPQKSQRSQDENPV
1 mg AS-62081 $105
MBP (6988)
YGSLPQKSQRSQDENPVVHF
1 mg AS-62085 $121
MBP (79 - 87)
DENPVVHFF
1 mg AS-62733 $71
MBP (84 - 97)
VVHFFKNIVTPRTP
1 mg AS-62731 $93
MBP (84 - 105)
VVHFFKNIVTPRTPPPSQGKGR
1 mg AS-62739 $181
MBP (87 - 99), human
VHFFKNIVTPRTP
1 mg AS-29211 $181
MBP (90 - 106)
Ac - FFKNIVTPRTPPPSQGK - NH2
1 mg AS-60977 $110
MBP (90 - 106), phosphorylated
FFKNIVTPRpTPPPSQGK - NH2
1 mg AS-60976 $154
MBP MAPK Substrate
APRTPGGRR
1 mg AS-27167 $49
MBP MAPK Substrate
APRTPGGRR
5 mg AS-27168 $193
MBP, MAPK Substrate, Biotinylated 1 mg AS-60747 $77
MBP, MAPK Substrate, 5 - TMR labeled
5 - TMR - APRTPGGRR
1 mg AS-60272-1 $308
MBP, MAPK Substrate, Biotinylated
Biotin - APRTPGGRR
5 mg AS-27170 $303
MBP, MAPK Substrate, Biotinylated, Phosphorylated
Biotin - APR - pT - PGGRR
1 mg AS-29877 $247
Biotin - LC - MBP Derivatized Peptide
Biotin - LC - FFKNIVTPRTPPPSQGK - NH2
1 mg AS-28231 $143
Biotin - LC - MBP Derivatized Peptide
Biotin - LC - FFKNIVTPRTPPPSQGK - NH2
5 mg AS-28232 $583
MBP, MAPK Substrate, Phosphorylated
APR - pT - PGGRR
1 mg AS-29939-1 $198
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