Assay Kits  >  Caspase Assay Kits
Apoptosis, a programmed, cell-autonomous death process, plays important roles in a variety of physiological and pathological events.1 These range from normal fetal development to diseases, such as cancer2 organ failure and neurodegenerative diseases. During apoptosis, caspases execute the disassembly of cellular components by proteolytic cleavage of a variety of substrates, such as poly-(ADP ribose) polymerase,3 DNA-dependent protein kinase (DNA-PK), topoisomerases, and protein kinase C delta.4 At least ten caspases have been discovered. Some of these caspases identify and cleave a specific peptide substrate, while others recognize the same peptide substrate.4
AnaSpec is pleased to showcase its line of SensoLyte® Caspase Assay Kits. With features that include one-step homogeneous assays, a convenient mix-and-read format, and highly sensitive fluorimetric components, SensoLyte® Caspase Assay Kits are an ideal solution for high-throughput screening.
References:
  1. Thornberry, NA. and Y. Lazebnik, Science 281, 1312-1316 (1998).
  2. Reed, JC. J. Clin. Oncol. 17, 2941-2953 (1999).

  3. Lazebnik, YA. et al. Nature 371, 346-347 (1994).

  4. Villa, P. et al. Trends Biochem. Sci. 22, 388-393 (1997).
 Product Size Catalog # US$  
SensoLyte® 520 Generic Caspase Assay Kit *Fluorimetric*  NEW 1 kit 72211 $435
SensoLyte® AFC Caspase Profiling Kit *Fluorimetric* 1 kit 71116 $627
SensoLyte® AFC Caspase Substrate Sampler Kit *Fluorimetric* 1 kit 71117 $501
SensoLyte® AMC Caspase Profiling Kit *Fluorimetric* 1 kit 71120 $627
SensoLyte® AMC Caspase Substrate Sampler Kit *Fluorimetric* 1 kit 71121 $501
SensoLyte® Homogeneous AFC Caspase - 8 Assay Kit
200 assays (96 - well plate)
1 kit 72088-200 $374
SensoLyte® Homogeneous AFC Caspase - 8 Assay Kit
100 assays (96 - well plate)
1 kit 72088-100 $247
SensoLyte® Homogeneous AMC Caspase - 3/7 Assay Kit
500 assays (96 - well plate)
1 kit 71118 $272
SensoLyte® Homogeneous AnaRed Caspase - 3/7 Assay Kit
500 assays (96 - well plate)
1 kit 71122 $374
SensoLyte® Homogeneous Rh110 Caspase - 3/7 Assay Kit
500 assays (96 - well plate)
1 kit 71141 $272
SensoLyte® Homogeneous AFC Caspase - 3/7 Assay Kit
500 assays (96 - well plate)
1 kit 71114 $272
  < Back