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Fluorescent Dyes  >  Reactive Fluorescent Dyes  >>  AMCA-X

Product Name AMCA - X
[6 - ((7 - Amino - 4 - methylcoumarin - 3 - acetyl)amino)hexanoic acid]
Size 25 mg
Catalog # AS-81207
US$ $121

Like AMCA (7-amino-4-methyl coumarin-3-acetic acid), AMCA-X emits in the blue region (440-460 nm) upon activation with UV light (350 nm). The acid is readily activated to form succinimidyl ester that reacts with lysine residues under mild conditions to form photostable amide links. AMCA fluorophores have high fluorescence quantum yields with the emission wavelength that perfectly matchs the mercury lamp irradiation spectrum. These two characteristics allow photographic exposure time of AMCA-labeled sections to be reduced to a quarter of that required for a corresponding FITC conjugate. In general, AMCA-immunoglobulin conjugates are not susceptible to minimal photobleaching and have a storage life at -20 oC for more than two years.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C desiccated and protected from light
References Eis PS and Lakowicz JR (1993). Time-resolved energy transfer measurements of donor-acceptor distance distributions and intramolecular flexibility of a CCHH zinc finger peptide. Biochemistry 32, 7981-93; Khalfan H, et al. (1986). Aminomethyl coumarin acetic acid: a new fluorescent labeling agent for proteins. Histochem J 18, 497-9.
Molecular Weight 346.38
Spectral Properties Abs/Em = 353/442 nm
Solvent System DMF or DMSO
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