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Fluorescent Dyes  >  Fluorescent Physiological and Neurological Indicators  >>  JC-1

Product Name JC - 1
[5,5',6,6' - tetrachloro - 1,1',3,3' - tetraethylbenzimidazolylcarbocyanine iodide]
CAS 47729-63-5
Size 5 mg
Catalog # AS-88060
US$ $175
Purity ≥95% by HPLC
Description

Widely used for measuring membrane potential of mitochondria; 585/520 Fluorescence ratio increases upon cell hyper-polarization.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C desiccated and protected from light
References 1. Cheng Z, et al. (2004). Am J Physiol Regul Integr Comp Physiol 286, R625-33.
2. Koo YE, et al. (2004). Anal Chem 76, 2498-505.
3. Wu CC, et al. (2004). Cereb Cortex 14, 543-54.
4. Suksaweang S, et al. (2004). Dev Biol 266, 109-22.
5. Iriyama A, et al. (2004). Invest Ophthalmol Vis Sci 45, 943-7.
6. Vest RS, et al. (2004). Biophys J 86, 2251-60.
7. Zhang X and Kirsch LE (2004). Pharm Dev Technol 9, 219-27.
8. Hefnawy MA and Abou-Zeid AM (2003). Acta Microbiol Pol 52, 53-64.
9. Jordan MB, et al. (2003). Blood 101, 594-601.
10. Bianchi L, et al. (2003). J Biol Chem 278, 12415-24.
11. deAzevedo LC, et al. (2003). J Neurobiol 55, 288-98.
12. Ramani K and Balasubramanian SV (2003). Biochim Biophys Acta 1618, 67-78.
Molecular Weight 652.224
Molecular Formula C25H27Cl4IN4
Spectral Properties Abs/Em = 514/529 nm
Solvent System DMSO
Product Citations Rama, D. et al. (2011). Expression of chemokine-like receptor 1 (CMKLR1) on J744A. 1 macrophages co-cultured with fibroblast and/or tumor cells: modeling the influence of microenvironment. Cell immunol 271, 134. doi: 10.1016/j.cellimm.2011.06.016.

Snyder, A. et al. (2010). HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells. AIDS 24, 1107.
     
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