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Assay Kits  >  MMP Assay Kits  >>  SensoLyte ® Plus 520 MMP-13 Assay Kit *Fluorimetric and Enhanced Selectivity*

Product Name SensoLyte ® Plus 520 MMP - 13 Assay Kit *Fluorimetric and Enhanced Selectivity*
Size 1 kit
Catalog # AS-72019
US$ $589

The SensoLyte® Plus 520 MMP-13 Assay Kit is designed for specifically detecting MMP-13 activity in biological samples which may contain multiple MMPs, such as culture medium, serum, plasma, synovial fluid, and tissue homogenate. A specific anti-MMP-13 monoclonal antibody is used in combination with a MMP fluorogenic substrate, 5-FAM/QXL®520 FRET peptide. The fluorescence signal is monitored at Ex/Em=490 nm/520 nm upon MMP-13-induced cleavage of the FRET substrate. Ample materials are provided to perform 96 assays in a 96-well format.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Product Citations Bartmann, J. et al. (2016) A novel role of MMP-13 for murine DC function: its inhibition dampens T-cell activation Int. Immunol doi: 10.1093/intimm/dxw008

Jackson, MT. et al. (2014). Activation of matrix metalloproteinases 2, 9, and 13 by activated protein C in human osteoarthritic cartilage chondrocytes. Arthritis Rheumatol. doi: 10.1002/art.38401.

Ozeki, N. et al. (2014). IL-1β-induced matrix metalloproteinase-13 is activated by a disintegrin and metalloprotease-28-regulated proliferation of human osteoblast-like cells. Exp Cell Res 323, 165.

Mak, I. et al. (2011). AP-1 as a regulator of MMP-13 in the stromal cell of giant cell tumor of bone. Biochem Res Int doi:10.1155/2011/164197.

Cowan, RW. et al. (2009). Collagenase expression and activity in the stromal cells from giant cell tumour of bone. Bone 44, 865. doi: 10.1016/j.bone.2009.01.393

Moor, AN. et al. (2009). Proteolytic activity in wound fluids and tissues derived from chronic venous leg ulcers. Wound Repair Regeneration 17, 832.

Salinas, C. et al. (2008). The enhancement of chondrogenic differentiation of human mesenchymal stem cells by enzymatically regulated RGD functionalities. Biomaterials 29, 2370.

Bai, L. et al. (2007). A role for CITED2, a CBP/p300 interacting protein, in colon cancer cell invasion. FEBS Lett 581, 5904.
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