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Peptides  >  Antimicrobial and Related Peptides  >>  Histatin-8 [Hemagglutination-Inhibiting Peptide (HIP)]

Product Name Histatin - 8 [Hemagglutination - Inhibiting Peptide (HIP)]
Size 1 mg
Catalog # AS-61002
US$ $99
Purity % Peak Area By HPLC ≥ 95%

Human salivary histatins (Hsts), which belong to a salivary polypeptide family, are small, cationic, histidine-rich proteins. They have potent bactericidal and antifungal activities against Candida albicans and Cryptococcus neoformans, and are therefore potential therapeutic reagents against Candida species.They kill fungal cells by binding to the cell membrane, internalizing, and disrupting volume regulatory mechanisms and mitochondrial function, leading to the production of reactive oxygen species and non-lytic loss.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References Yoshida, M. et al. Biol. Pharm. Bull. 24, 1267 (2001); Ahmad, M. et. al. J. Histochem. Cytochem. 52, 361 (2004).
Molecular Weight 1562.7
(One-Letter Code)
(Three-Letter Code)
H - Lys - Phe - His - Glu - Lys - His - His - Ser - His - Arg - Gly - Tyr - OH
Product Citations Walters, S.M. et al. (2010). Antibiotic-induced Porphyromonas gingivalis LPS release and inhibition of LPS-stimulated cytokines by antimicrobial peptides. Peptides doi:10.1016/j.peptides.2010.06.001.
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