Myelin oligodendrocyte glycoprotein (MOG) is a member of the immunoglobulin superfamily and is expressed exclusively in the central nervous system (1-3). MOG (35-55) is able to induce autoantibody production and relapsing-remitting neurological disease causing extensive plaque-like demyelination (1-2). Autoantibody response to MOG (35-55) has been observed in multiple sclerosis (MS) patients and MOG (35-55)-induced experimental autoimmune encephalomyelitis (EAE) C57/BL6 mice and Lewis rats (1-4).
Every lot of MOG (35-55) peptide is tested and proven to induce EAE. For the EAE results of the current lot, please email email@example.com.
1. Slavin, A. et al. Autoimmunity28, 109 (1998). 2. Ichikawa, M. et al. Cellular Immunol191, 97 (1999). 3. Kennel De March, A. et al. J Neuroimmunol135, 117 (2003). 4. Robinson, W. et al. Nat Biotech21, 1033 (2003).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Met - Glu - Val - Gly - Trp - Tyr - Arg - Ser - Pro - Phe - Ser - Arg - Val - Val - His - Leu - Tyr - Arg - Asn - Gly - Lys - OH