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Fluorescent Dyes  >  Fluorescent Biopolymers  >>  Beta-Amyloid (1-42), HiLyteᵀᴹ Fluor 555-labeled, Human

Product Name Beta - Amyloid (1 - 42), HiLyteᵀᴹ Fluor 555 - labeled, Human
Size 0.1 mg
Catalog # AS-60480-01
US$ $242
Purity % Peak Area By HPLC ≥ 95%

This is a fluorescent (HiLyte™ Fluor 555)-labeled ß-Amyloid peptide, Abs/Em=551/567 nm.

Fgure 1. Absoprtion and emission spectra of HiLyte™ Fluor 555 labeled β-Amyloid (1-42).

Figure 2. Staining pattern of HiLyte™ Fluor 555 labeled Aβ (1-42) peptide on an AD (A) and a normal brain (B). Images courtesy of Dr. Jian-Ping Guo in Dr. Patrick L. McGeer’s lab, University of British Columbia, Vancouver, Canada.

Images Beta-Amyloid (1-42), HiLyteᵀᴹ  Fluor 555-labeled, Human
Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20°C
Molecular Weight 5366.57
(One-Letter Code)
(Three-Letter Code)
HiLyte™ Fluor 555 - Asp - Ala - Glu - Phe - Arg - His - Asp - Ser - Gly - Tyr - Glu - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - Ile - Ala - OH
Product Citations Maneshi, MM. et al. (2018). Enantiomeric Aβ peptides inhibit the fluid shear stress response of PIEZO1. Sci Rep 8(1):14267. doi: 10.1038/s41598-018-32572-2.

Condello, C. et al. (2015). Microglia constitute a barrier that prevents neurotoxic protofibrillar ​Aβ42 hotspots around plaques. Nat Commun doi:10.1038/ncomms7176.

Epelbaum, S. et al. (2015). Acute amnestic encephalopathy in amyloid-ß oligomers injected mice is due to their widespread diffusion in vivo. Neurobiol Aging doi: 10.1016/j.neurobiolaging.2015.03.005.

Sonkar, VK. et al. (2014). Amyloid β peptide stimulates platelet activation through RhoA-dependent modulation of actomyosin organization. FASEB J 28, 1819. doi: 10.1096/fj.13-243691.

Quinn, SD. et al. (2013). Real-time probing of β-amyloid self-assembly and inhibition using fluorescence self-quenching between neighbouring dyes. Mol BioSyst doi: 10.1039/C3MB70272C.

Cizas, P. et al. (2010). Size-dependent neurotoxicity of β-amyloid oligomers. Arch Biochem Biophys 496, 84. doi: 10.1016/j.abb.2010.02.001

Liu, Z. et al. (2010). CX3CR1 in microglia regulates brain amyloid deposition through selective protofibrillar amyloid-β phagocytosis. J Neurosci 30, 17091. doi: 10.1523/JNEUROSCI.4403-10.2010.

Jiang, M. & G. Chen (2009). Ca2+ regulation of dynamin-independent endocytosis in cortical astrocytes. J. Neurosci. 29, 8063.

Widenbrant, MJO. et al. (2006). Lipid-Induced β-Amyloid Peptide Assemblage Fragmentation. Biophys J 91, 4071. doi: 10.1529/biophysj.106.085944.
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