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Fluorescent Dyes  >  Enzyme Detection Reagents  >>  NFF-3

Product Name NFF - 3
Mca - RPKPVE - Nva - WR - K(Dnp) - NH2
Size 1 mg
Catalog # AS-27114
US$ $99
Purity % Peak Area By HPLC ≥ 95%

NFF-3 is hydrolyzed rapidly by MMP-3 (kcat/Km = 218,000 s-1 M-1) and very slowly by MMP-9 (kcat/Km = 10,100 s-1 M-1), but no significant hydrolysis by MMP-1 and MMP-2. It is one of the few synthetic substrates selectively hydrolyzed by certain members of the MMP family and thus has important applications for the differentiation of MMP-3 activity from that of other MMPs. Abs/Em = 325/393 nm.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20C
References Ref: Bremer, C. et al. Acad. Radiol. 9 Suppl 2, S314 (2002); Nagase, H. et al. J. Biol. Chem. 269, 20952 (1994).
Molecular Weight 1675.9
(One-Letter Code)
(Three-Letter Code)
Mca - Arg - Pro - Lys - Pro - Val - Glu - Nva - Trp - Arg - Lys(Dnp) - NH2
Product Citations Kadonosono, T. et al. Appl. Microbio. Biotech. 75, 1285 (2007).
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