Fluorescent Dyes  >  Fluorescent Physiological and Neurological Indicators  >>  SensoLyte ® AFC Caspase Profiling Kit *Fluorimetric*

Caspases play important roles in apoptosis and cell signaling. They are also identified as drug-screening targets. AFC-based substrates yield blue fluorescence upon protease cleavage. They are widely used to monitor caspase activity.

The SensoLyte^® Caspase Profiling Kit contains a series of AFC-based peptide substrates (Ex/Em=380 nm/500 nm) as fluorogenic indicators for assaying caspase protease activities. The kit contains a well-designed plate in which a series of AFC-based caspase substrates are coated with both positive and negative controls. It provides the best solution for profiling caspases or caspase inhibitors.

The kit contains:
• A 96-well plate coated with a series of AFC-based caspase substrates along with various controls*
• Cell lysis buffer
• Assay buffer
• AFC (fluorescence reference standard for calibration)
• A detailed protocol A detailed protocol

*384-well plate format is available on a custom basis.

Kit Size: 2 plates