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Peptides  >  Anti-Inflammatory Peptides  >>  WP9QY, TNF-alpha Antagonist

Product Name WP9QY, TNF - alpha Antagonist
YCWSQYLCY (Disulfide bridge: 2 - 8)
Size 1 mg
Catalog # AS-62621
US$ $132
Purity % Peak Area By HPLC ≥ 95%

This cyclic peptide is designed to mimic the most critical tumor necrosis factor (TNF) recognition loop on TNF receptor I. It prevents interactions of TNF with its receptor. This TNF antagonist is a useful template for the development of small molecular inhibitors to prevent both inflammatory bone destruction and systemic bone loss in rheumatoid arthritis.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References Saito, H. et al. Arthritis Rheum. 56, 1164 (2007).
Molecular Weight 1226.4
(One-Letter Code)
YCWSQYLCY (Disulfide bridge: 2-8)
(Three-Letter Code)
H - Tyr - Cys - Trp - Ser - Gln - Tyr - Leu - Cys - Tyr - OH (Disulfide bridge: 2 - 8)
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