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Amino Acids  >  Unusual Amino Acids  >  Azide and Alkyne containing Amino Acids  >>  Fmoc-Lys(N3)-OH

Product Name Fmoc - Lys(N3) - OH
Fmoc - azidolysine; Fmoc - lys(azide); Fmoc - lysine azide
CAS 159610-89-6
Size 250 mg
Catalog # AS-53100-F025
US$ $154
Purity ≥95% by HPLC

An unusual amino acid used in Solid Phase Peptide Synthesis (SPPS) for the synthesis of side-chain modified peptides and proteins.1 The side-chain azido (N3) group is stable in trifluoroacetic acid (TFA) or piperidine (Pip), two reagents commonly used in SPPS. The azido group can be readily converted to an amine on the solid phase or in solution via the Staudinger reduction.2

Detailed Information Material Safety Data Sheets (MSDS)
Storage 4C
References 1. Vallee, M. R. J.; Majkut, P.; Wilkening, C. W.; Muller, G.; Hackenberger, C. P. R. Staudinger-Phosphonite Reactions for the Chemoselective Transformation of Azido-Containing Peptides and Proteins.Org. Lett. 2011 (13) 5440-5443.
2. Staudinger, H.; Meyer, J. UberneueorganischePhosphorverbindungen III. Phosphinmethylenederivative und Phosphinimine. Helvetica Chim. Acta. 1919 (2) 635-646.
Molecular Weight 394.42
Molecular Formula C21H22N4O4
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