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Peptides  >  Anti-Inflammatory Peptides  >>  Linear C5a Receptor Antagonist, human, rat

Product Name Linear C5a Receptor Antagonist, human, rat
FKP - (D - Cha) - Wr
Size 1 mg
Catalog # AS-65122
US$ $99
Purity % Peak Area By HPLC ≥ 95%

This linear peptide is derived from the C-terminus of the chemokine, complement fragment 5 anaphylatoxin (C5a). This peptide functions to inhibit C5a binding and function at human and rat C5a receptors. C5a is crucial to triggering cellular immune responses and its overexpression is involved in arthritis, Alzheimer’s disease, cystic fibrosis, systemic lupus erythematosus, and other immunoinflammatory diseases

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20°C
References Higginbottom, A. J Biol Chem 280, 17831 (2005); Buck, E. et al. PNAS 102, 2719 (2005).
Molecular Weight 886.1
(One-Letter Code)
(Three-Letter Code)
H - Phe - Lys - Pro - D - Cha - Trp - D - Arg - OH
Product Citations Spaan, A. et al. (2015). Differential Interaction of the Staphylococcal Toxins Panton–Valentine Leukocidin and γ-Hemolysin CB with Human C5a Receptors. JofI 195(3) 1034. DOI: https://doi.org/10.4049/jimmunol.1500604
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