AggreSureᵀᴹ β - Amyloid (1 - 40), human DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
0.25 mg NET peptide
AggreSure™ beta-Amyloid (1-40) peptide is pretreated and tested for aggregation using SensoLyte® ThT Aβ40 Aggregation kit (Cat# 72213). Aggregation is guaranteed.
AS-72215 fig. 1
Figure 1. An increase of fluorescence signal is correlated with an increase of Aβ40 fibril formation. Phenol Red, 0-Vanillin, Dopamine, and Tannic Acid were added at 50 μM final concentration to inhibit Aβ40 aggregation. Fluorescence signal was monitored at Ex/Em= 440/484 nm every 5 minutes at 37ºC with 15 seconds shaking between reads (SpectraMax M5e fluorimeter, Molecular Devices).
H - Asp - Ala - Glu - Phe - Arg - His - Asp - Ser - Gly - Tyr - Glu - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - OH