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Peptides  >  Cyclic Peptides  >   Disulfide Cyclized Peptides  >>  Amylin (1-37), human
Product Name Amylin (1 - 37), human
KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY (Disulfide bridge: 2 - 7)
Size 1 mg
Catalog # AS-60804
US$ $303
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is a major constituent of protein deposits identified in the Islets of Langerhans of patients with noninsulin-dependent diabetes mellitus.
Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20°C
References Ref: Jhamandas, J. et al. J. Neurophysiol. 89, 2923 (2003).
Molecular Weight 3904.5
Sequence
(One-Letter Code)		 KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY (Disulfide bridge: 2-7)
Sequence
(Three-Letter Code)		 H - Lys - Cys - Asn - Thr - Ala - Thr - Cys - Ala - Thr - Gln - Arg - Leu - Ala - Asn - Phe - Leu - Val - His - Ser - Ser - Asn - Asn - Phe - Gly - Ala - Ile - Leu - Ser - Ser - Thr - Asn - Val - Gly - Ser - Asn - Thr - Tyr - OH (Disulfide bridge: 2 - 7)
Product Citations Pilkington, EH. Et al. (2017). Effects of Protein Corona on IAPP Amyloid Aggregation, Fibril Remodelling, and Cytotoxicity. Sci Rep 7(1):2455. doi: 10.1038/s41598-017-02597-0.

Wang, M. et al. (2017). Differential effects of silver and iron oxide nanoparticles on IAPP amyloid aggregation. Biomater Sci. 5(3):485-493. doi: 10.1039/c6bm00764c.

Su, L. et al. (2017). The effect of aluminum ion on the aggregation of human islet amyloid polypeptide (11-28). Acta  Biochim Biophys Sin (Shanghai). 49(4):355-360. doi:10.1093/abbs/gmx015

Ly, H. et al. (2017). Brain microvascular injury and white matter disease provoked by diabetes-associated hyperamylinemia. Ann Neurol. doi:10.1002/ana.24992.
     
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