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Antibodies  >  OptimAb Antibodies  >>  OptimAbᵀᴹ Neuronal Class III beta-Tubulin , Monoclonal Antibody, purified

Product Name OptimAbᵀᴹ Neuronal Class III beta - Tubulin , Monoclonal Antibody, purified
Clone: TUJ1; Host: Mouse, Monoclonal Antibody
Size 100 g/100 l
Catalog # MMS-435P-100
US$ $337
Description

This antibody was raised against microtubules derived from rat brain. It is highly reactive to neuron specific Class III -tubulin (III), and does not cross-react on -tubulin found in glial cells.
Tubulin is the main component of microtubules. In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation. Mutations in this gene cause congenital fibrosis of the type 3 extraocular muscles. Tubulin beta 3 (TUBB3) is also found in a wide range of tumors and is used as a predictive and prognostic marker in various tumors.

Host:Mouse
Clone: TUJ1
Isotype: IgG2a
Reactivity: Mammalian
Immunogen: TUJ1 was raised against microtubules derived from rat brain
Concentration:1 mg/mL
Formulation:PBS + 0.03% Thimerosal; The Ab is purified
Applications:The Ab is effective in immunoblotting (WB), immunostaining (IHC, ICC) and immunoprecipitation (IP).
Working Dilutions:WB: 1/1.000 (predicted MW = 50 kDa)

Detailed Information Datasheet
Storage 4C
References 1, Mozzetti S et al. (2005) Clin. Cancer Res. 11(1): 298-305.
2, Brown NL et al. (2001) Development 128(13): 2497-2508.
3, Jepsen K et al. (2000) Cell 102(6): 753-763.
     
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