OptimAbᵀᴹ Neuronal Class III beta - Tubulin , Monoclonal Antibody, purified Clone: TUJ1; Host: Mouse, Monoclonal Antibody
200 µg/200 µL
This antibody was raised against microtubules derived from rat brain. It is highly reactive to neuron specific Class III ß-tubulin (ßIII), and does not cross-react on ß-tubulin found in glial cells. Tubulin is the main component of microtubules. In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation. Mutations in this gene cause congenital fibrosis of the type 3 extraocular muscles. Tubulin beta 3 (TUBB3) is also found in a wide range of tumors and is used as a predictive and prognostic marker in various tumors.
Host:MouseClone: TUJ1Isotype: IgG2aReactivity: MammalianImmunogen: TUJ1 was raised against microtubules derived from rat brainConcentration:1 mg/mLFormulation:PBS + 0.03% Thimerosal; The Ab is purifiedApplications:The Ab is effective in immunoblotting (WB), immunostaining (IHC, ICC) and immunoprecipitation (IP).Working Dilutions:WB: 1/1.000 (predicted MW = 50 kDa) IHC: 1/500 - 1/5.000 ICC: 1/1.000 - 1/5.000