OptimAbᵀᴹ Neuronal Class III beta - Tubulin Polyclonal Antibody, purified Host: Rabbit, Polyclonal Antibody
50 µg/50 µL
This antibody was raised against microtubules derived from rat brain. It is highly reactive to neuron specific Class III ß-tubulin (ßIII), but does not cross-react on ß-tubulin found in glial cells. Tubulin is the main component of microtubules. In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation. Mutations in this gene cause congenital fibrosis of the type 3 extraocular muscles. Tubulin beta 3 (TUBB3) is also found in a wide range of tumors and is used as a predictive and prognostic marker in various tumors.
Host:RabbitClone: N/AIsotype: N/AReactivity: MammalianImmunogen: This pAb was raised against microtubules derived from rat brainConcentration:1 mg/mLFormulation:PBS + 50% Glycerol + 0.03% Thimerosal. The Ab was purified by affinity chromatographyApplications:The Ab is effective in immunoblotting (WB) and immunostaining (IHC, ICC).Working Dilutions:WB: 1/5.000 (predicted MW: 50 kDa) ICC: 1/1.000 - 1/2.500 IHC: 1/5.000 - 1/10.000
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