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Antibodies  >  OptimAb Antibodies  >>  OptimAbᵀᴹ sAPPbeta Polyclonal Antibody, purified

Product Name OptimAbᵀᴹ sAPPbeta Polyclonal Antibody, purified
Host: Rabbit, Polyclonal Antibody
Size 50 µg/50 µL
Catalog # SIG-39138-050
US$ $661

Beta-Amyloid forms are deposited in the CNS of patients with Alzheimer’s disease and Down’s syndrome. Biochemical analysis of the amyloid peptides isolated from Alzheimer’s disease brain indicates that Beta-Amyloid (1-42) is the principal species associated with senile plaque amyloids, while Beta-Amyloid (1-40) is more abundant in cerebrovascular amyloid deposits. Both result from the cleavage of Amyloid Precursor Protein (APP) by secretases. This rabbit anti-sAPPß pAb is specific for the soluble fragment of APP, cleaved N-terminus to the beta-secretase cleavage site. It has negligible cross reactivity to sAPP? or full length APP.

Clone: N/A
Isotype: N/A
Reactivity: Human, Rodent
Immunogen: nd
Concentration:1 mg/mL
Formulation:PBS (no preservatives). The Ab is affinity purified
Applications:The Ab is effective in immunoblotting (WB), immunohistochemistry (IHC) and ELISA.
Working Dilutions:WB: 1/500 - 1/1.000
ELISA: 2.5 - 250 ng/ml
Strage Instruction:Store at 4°C; do not store antibody diluted below 50µg/ml in the absence of carrier protein (e.g. add 2% BSA)

Detailed Information Datasheet
Storage 4°C
References Freude et al. (2011) J. Biol. Chem. 286(27): 24264-24274.
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