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Antibodies  >  OptimAb Antibodies  >>  OptimAbᵀᴹ Tau , Monoclonal Antibody, purified

Product Name OptimAbᵀᴹ Tau , Monoclonal Antibody, purified
Clone: Tau 5; Host: Mouse, Monoclonal Antibody
Size 50 µg/100 µl
Catalog # SIG-39413-050
US$ $269
Description

Tau proteins belong to the microtubule-associated protein (MAP) family and are involved in the pathogenesis of Alzheimer’s disease. In the human brain, there are six Tau isoforms ranging from 352 to 441 amino acids in length. These isoforms vary at the carboxy-terminus according to the presence of either three repeat or four repeat domains (R1-R4), in addition to the presence or absence of one or two insert domains at the amino-terminus. This antibody is specific for an epitope that lies between amino acids 210-230 of human Tau.

Host:Mouse
Clone: Tau 5
Isotype: IgG1
Reactivity: Human
Immunogen: nd
Concentration:0.5 mg/mL
Formulation:PBS (with no preservatives). The Ab was purified on Protein G
Applications:The Ab is effective in immunoblotting (WB), ELISA and immunohistochemistry (IHC).
Working Dilutions:WB: 1/500 - 1/1.000
IHC: 1/25 - 1/40
Strage Instruction:Store at 4°C; do not store antibody diluted below 50µg/ml in the absence of carrier protein (e.g. add 2% BSA)

Detailed Information Datasheet
Storage 4°C
References 1, Guillozet-Bongaarts AL et al. (2005) Neurobiol. Aging 26(7): 1015-1022.
2, Horowitz PM et al. (2004) J. Neurosci. 24(36): 7895-7902.
3, Garcia-Sierra F et al. (2003) J. Alzheimers Dis. 5(2): 65-77.
     
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