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Antibodies  >  OptimAb Antibodies  >>  OptimAbᵀᴹ Nonmuscle Myosin Heavy Chain II-A Polyclonal Antibody, purified

Product Name OptimAbᵀᴹ Nonmuscle Myosin Heavy Chain II - A Polyclonal Antibody, purified
Host: Rabbit, Polyclonal Antibody
Size 50 g/50 L
Catalog # PRB-440P-050
US$ $282

Nonmuscle Myosin II Heavy Chain Isoform A (MHCA, NMHC IIA, Myosin-9) is a member of the myosin family. Myosin II (also known as conventional myosin) is the myosin type responsible for producing muscle contraction in muscle cells.
Myosin II contains two heavy chains (MHC), each about 2000 amino acids in length, which constitute the head and tail domains. It also contains 4 light chains (MLC), which bind the heavy chains in the neck region between the head and tail. There are 3 forms of myosin II: IIA, IIB and IIC.

Host: Rabbit
Clone: N/A
Isotype: N/A
Reactivity: Human, Rodent, Bovine
Immunogen: This antibody was raised against the peptide GKADGAEAKPAE corresponding to the C-terminus of human nonmuscle myosin heavy chain isoform A
Concentration:1 mg/mL
Formulation:PBS + 0.03% Thimerosal; The Ab is affinity purified
Applications: The Ab is effective in immunoblotting (WB) and immunofluorescence (IF)
Working Dilutions: WB: 1/1,000 (predicted MW = 200 kDa); IF: 1/500

Detailed Information Datasheet
Storage 4C
References 1, Ma X et al. (2007) Mol. Biol. Cell. 18(6): 2305-2312.
2, Golomb E et al. (2004) J. Biol. Chem. 279(4): 2800-2808.
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