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Antibodies  >  OptimAb Antibodies  >>  OptimAbᵀᴹ Nuclear Pore Complex Proteins , Monoclonal Antibody, purified

Product Name OptimAbᵀᴹ Nuclear Pore Complex Proteins , Monoclonal Antibody, purified
Clone: MAb414; Host: Mouse, Monoclonal Antibody
Size 100 g/100 l
Catalog # MMS-120P-100
US$ $306
Description

MAb414 is a reliable general purpose monoclonal antibody which recognizes a related family of NPC proteins. This antibody is ideal for studying the morphology and composition of the nucleus and nuclear envelope. It is also useful in studying changes in the nuclear structure during mitosis and meiosis.
MAb414 is believed to recognize the repeated FXFG repeat sequence in nucleoporins including p62, p152 and p90 and other proteins.

Host:Mouse
Clone: MAb414
Isotype: IgG1
Reactivity: Vertebrate, Xenopus, Yeast
Immunogen: The antibody was raised using a nuclear pore complex mixture
Concentration:1 mg/mL
Formulation:PBS + 0.03% Thimerosal; The Ab was purified on Protein G
Applications:The Ab is effective in immunoblotting (WB), immunohistochemistry (IHC), immunofluorescence (IF), immunoprecipitation (IP) and immunoelectron microscopy (IEM).
Working Dilutions:WB: 1/5.000 (predicted MW = 62 kDa)
IF: 1/5.000
IHC: 1/500
IP: 1/5.000
IEM: 1/5.000

Detailed Information Datasheet
Storage 4C
References 1, Kimura T et al. (2003) Mol. Cell. Biol. 23: 1304-1315.
2, Lopez-Soler RI et al. (2001) J. Cell. Biol. 154(1): 61-70.
3, Aris JP & Blobel G (1989) Y J. Cell. Biol. 108: 2059-2067.
4, Davis LI & Blobel G (1987) Proc. Natl. Acad. Sci USA 84: 7552-7556.
5, Davis LI & Blobel G (1986) Cell 45: 699-709.
6, Blobel G (1985) Proc. Natl. Acad. Sci. USA 82: 8527-8529.
     
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