This polyclonal Ab is used for the qualitative identification of fillagrin in human biological samples using immunohistochemistry (IHC) methods. The clinical interpretation of any staining or its absence should be complemented by morphological studies and proper controls and should be evaluated within the context of the patient's clinical history and other diagnostic tests by a qualified pathologist.
Host:RabbitClone: N/AIsotype: N/AReactivity: Human, Mouse, PrimateImmunogen: This monospecific polyclonal antibody was raised against a peptide corresponding to residues 24-39 in the partial sequence of filaggrinConcentration:1 mg/mLFormulation:PBS + 0.03% Thimerosal. The Ab was purified using peptide affinity chromatographyApplications:For research use applications, the Ab is effective in immunoblotting (WB), immunofluorescence (IF) and immunohistochemistry (IHC).
1, Hu Y et al. (2001) Nature 410: 710-714.2, Yuspa SH et al. (1989) J. Cell. Biol. 109: 1207-1217.3, Roop DR et al. (1984) J. Biol. Chem. 259: 8037-8040.
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