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Antibodies  >  OptimAb Antibodies  >>  OptimAbᵀᴹ Pax-2 Polyclonal Antibody, purified

Product Name OptimAbᵀᴹ Pax - 2 Polyclonal Antibody, purified
Host: Rabbit, Polyclonal Antibody
Size 100 g/100 l
Catalog # PRB-276P-100
US$ $294

Paired box (Pax) proteins are tissue-specific transcription factors that contain a paired domain and a homeodomain. They are produced during embryogenesis in a temporally and spatially restricted manner in the developing neural tube. Pax-2 has been associated to kidney and optic nerve development. This antibody recognizes Pax-2A and Pax-2B (two products of the Pax-2 gene). When conjugated to agarose beads, this Ab has been used to immunoprecipitate DNA sequences which are the target of Pax-2.

Clone: N/A
Isotype: N/A
Reactivity: Human, Mouse, Chicken, Xenopus and Zebrafish
Immunogen: This pAb was raised against a recombinant protein corresponding to amino acids 188-385 from Pax-2
Concentration:1 mg/mL
Formulation:PBS + 0.03% Thimerosal; The Ab is purified
Applications:The Ab is effective in immunoblotting (WB), immunohistochemistry (IHC), immunoprecipitation and DNA band supershift experiments. Positive control tissues: normal kidney, renal adenocarcinoma.
Working Dilutions:WB: 1/250 - 1/1.000 (predicted MW = 44 kDa)
IHC: 1/100
Gel shifts: 1/10

Detailed Information Datasheet
Storage 4C
References 1, Hammes A et al. (2001) Cell 106: 319-329.
2, Phelps DE & Dressler GR (1996) J. Biol. Chem. 271: 7978-7985.
3, Rothenpieler UW & Dressler GR (1993) Development 119: 711-720.
4, Dressler GR et al. (1993) Nature 362: 65-67.
5, Dressler GR & Douglass EC (1992) Proc. Natl. Acad. Sci. USA 89: 1179-1183.
6, Puschel AW et al. (1992) Mech. Dev. 38: 197-208.
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