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Peptides  >  Cardiovascular Related Peptides  >>  Biotin-LC-Angiotensin II

Product Name Biotin - LC - Angiotensin II
Biotin - LC - DRVYIHPF
Size 5 mg
Catalog # AS-60276-5
US$ $264
Purity % Peak Area By HPLC ≥ 95%

This octapeptide Angiotensin II, DRVYIHPF, is biotinylated on the N-terminus via an LC (long chain, also known as 6-Aminohexanoyl, 6-Aminocaproyl or Ahx) linker. It can be used in ELISA assay. Angiotensin II (Ang II) exerts a wide range of effects on the cardiovascular system. It is also implicated in the regulation of cell proliferation, fibrosis and apoptosis. Ang II is formed by cleavage of Ang I by the angiotensin-converting enzyme (ACE) or chymases. Human heart chymase, a chymotrypsin-like serine proteinase, hydrolyzes the Phe8-His9 bond to yield the octapeptide hormone angiotensin II and His-Leu.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References 1, Cobb, C. et al. Gen Comp Endocrinol 127, 8 (2002)
2, Lundequist, A. et al. J Biol Chem 279, 32339 (2004)
3, Kinoshita, A. et al. J Biol Chem 266, 19192 (1991)
4, Spyroulias, G. et al. Eur J Biochem 270, 2163 (2003).
Molecular Weight 1385.7
(One-Letter Code)
(Three-Letter Code)
Biotin - LC - Asp - Arg - Val - Tyr - Ile - His - Pro - Phe - OH
Product Citations Young, SH. & E. Rozengurt (2006). Qdot nanocrystal conjugates conjugated to bombesin or ANG II label the cognate G protein-coupled receptor in living cells. Am J Physiol-Cell Physiol 290, C728. doi: 10.1152/ajpcell.00310.2005.
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