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Peptides  >  Diabetes Related Peptides  >>  GLP-1(9-36), amide, human

Product Name GLP - 1(9 - 36), amide, human
Size 1 mg
Catalog # AS-65070
US$ $203
Purity % Peak Area By HPLC ≥ 95%

GLP-1 (9-36) is the result of the rapid degradation of GLP-1 (7-36)amide, by the enzyme dipeptidyl peptidase IV (DPP-4), which is widely expressed in a number of sites, including the endothelial cells of small gut arterioles. GLP-1 (9-36) accounts for the majority of GLP-1 that reaches the system circulation. Whereas GLP-1 (7-36) amide stimulates glucose-dependent insulin secretion and inhibits glucagon secretion, GLP-1(9-36)amide administration had no effect on glucose clearance or insulin secretion in humans. GLP-1(9-36)amide however was shown to exert cardioprotective actions in rodent hearts.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References John, H. et al. Eur J Med Res 13, 73 (2008)
Elahi, D. et. al. Obesity (Silver Spring) 16, 1501 (2008), doi: 10.1038/oby.2008.229
Ban, K. et. al. Endocrinol 151, 1520 (2010), doi: http://dx.doi.org/10.1210/en.2009-1197
Molecular Weight 3089.5
(One-Letter Code)
(Three-Letter Code)
H - Glu - Gly - Thr - Phe - Thr - Ser - Asp - Val - Ser - Ser - Tyr - Leu - Glu - Gly - Gln - Ala - Ala - Lys - Glu - Phe - Ile - Ala - Trp - Leu - Val - Lys - Gly - Arg - NH2
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