Peptides  >  Myelin Oligodendrocyte Glycoprotein (MOG)/Myelin Basic Proteins (MBP)
Myelin Oligodendrocyte Glycoprotein (MOG), a 26- to 28-kDa protein, is a member of the immunoglobulin superfamily. It is expressed exclusively in the central nervous system (CNS), specifically on the surface of myelinating oligodendrocytes and external lamellae of myelin sheath. Although MOG protein constitutes only 0.01-0.05% of the CNS myelin proteins, it was demonstrated that MOG protein is a crucial autoantigen for multiple sclerosis in humans and experimental autoimmune encephalomyelitis (EAE) in rodents and monkeys.

Myelin Basic Protein (MBP) is the major constituent of the CNS myelin synthesized by oligodendrocytes and Schwann cells. MBP, PLP (proteolipid proteins) and MOG (myelin oligodendrocyte glycoprotein) are potential primary encephalitogenic target antigens in multiple sclerosis.


Ref: Linares, D. et al. Protein Expression and Purif. 34, 249 (2004); Bettadapura, J. et al. J. Neurochem. 70, 1593 (1998); Oliver, AR. et al J. Immunol. 171, 462 (2003); Von Budingen, H-C. et al. J. Clin. Immunol. 21, 155 (2001); Lyons, J-A. et.al. Eur. J. Immunol. 29, 3432 (1999); Von Budingen, H-C. et.al. Eur. J. Immunol. 34, 2072 (2003); Grima, B. et al. J. Neurochem. 59, 2318 (1992); Tabira, TJ. and I. Kira, Strain and species differences of encephalitogenic determinants of myelin basic protein and proteolipid apoprotein. RE. Martenson, ed. Myelin: Biology and Chemistry 783. CRC Press, Boca Raton (1992). De Rosbo, NK. et al. J. Immunol. 173, 1426 (2004).

Learn More: SensoLyte MOG Kits, MOG 35-55 peptide, and MOG Recombinant Proteins
 Product Size Catalog # US$  
MOG (35 - 55), mouse, rat
MEVGWYRSPFSRVVHLYRNGK
1 mg AS-60130-1 $147
MOG (35 - 55), mouse, rat
MEVGWYRSPFSRVVHLYRNGK
5 mg AS-60130-5 $458
MOG (35 - 55), mouse, rat
MEVGWYRSPFSRVVHLYRNGK
10 mg AS-60130-10 $824
MOG (35 - 55), human
MEVGWYRPPFSRVVHLYRNGK
1 mg AS-63918 $150
MOG (89 - 113), human
RFSDEGGFTCFFRDHSYQEEAAMEL
1 mg AS-64218 $204
MOG (92 - 106)
DEGGYTCFFRDHSYQ
1 mg AS-62732 $96
MBP (4 - 14), bovine, MBP (3 - 13), mouse
QKRPSQRSKYL
5 mg AS-22916 $199
MBP (69 - 85), guinea pig
YGSLPQKSQRSQDENPV
1 mg AS-62081 $108
MBP (85 - 98), guinea pig, MBP (86 - 99), human, MBP (83 - 96) mouse
VVHFFKNIVTPRTP
1 mg AS-62731 $96
MBP (85 - 106) guinea pig, MBP (86 - 107), human
VVHFFKNIVTPRTPPPSQGKGR
1 mg AS-62739 $186
MBP (84 - 96), mouse, MBP (86 - 98), guinea pig, MBP (87 - 99), human
VHFFKNIVTPRTP
1 mg AS-29211 $186
MBP (88 - 104), guinea pig, MBP (89 - 105), human, MBP (86 - 102), mouse
Ac - FFKNIVTPRTPPPSQGK - NH2
1 mg AS-60977 $113
MBP MAPK Substrate
APRTPGGRR
5 mg AS-27168 $199
MBP, MAPK Substrate, Biotinylated 1 mg AS-60747 $79
MBP, MAPK Substrate, Biotinylated, Phosphorylated
Biotin - APR - pT - PGGRR
1 mg AS-29877 $254
Biotin - LC - MBP Derivatized Peptide
Biotin - LC - FFKNIVTPRTPPPSQGK - NH2
1 mg AS-28231 $147
Biotin - LC - MBP Derivatized Peptide
Biotin - LC - FFKNIVTPRTPPPSQGK - NH2
5 mg AS-28232 $595
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