Peptides  >  Histones
The core histones (H2A, H2B, H3 and H4) act as spools around which DNA winds. Covalent modification on the amino terminal of the core histones through de/acetylation, de/methylation and de/phosphorylation affect chromatin structure and exquisitely regulate gene expression.1-3 Histone hyperacetylation is correlated with increased transcription, whereas hypoacetylation correlates with transcriptional repression.2

AnaSpec, the world’s largest provider of on-demand GO peptides is pleased to announce the rapid expansion of our histone peptide selection. Histone GO® Peptides include sequences that are acetylated and di- or tri-methylated. For sequences that are not found on this list, please request a custom quotation here

1. Jenuwein, T. and CD. Allis Science 293, 1074 (2001).
2. Sterner, DE. et al. Microbiol. Mol. Biol. Rev. 64, 435 (2000).
3. Lachner, M. et al. J. Cell Sci. 116, 2117 (2003).

Related Kits SensoLyte® fluorimetric assay kits for Epigenetics research

Modified & Non-Modified Histone Peptides:
Histone H1 Peptides
Histone H2A Peptides
Histone H2B Peptides
Histone H3 Peptides
Histone H4 Peptides
Histone Related Substrates
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